She looks a lot like Irma, only taller and with longer hair. Her personality is similar to Irma's too, but she is a little more mature. Anna is a little oblivious to Chris's bad behavior, and seems to protect him from his sister. Irma has hinted that she gets embarrassed by Anna in Season 1 episodes: "Happy Birthday Will" and "Parents' Night". She likes to party, although in a "lame" way. Anna is proud of her husband being a police officer. She likes to go to the beach as shown in "I is for Illusion" and "J is for Jewel". She was attacked by Shagon in "M is for Mercy". Her final appearance is in "W is for Witch".
- Tom Lair (husband)
- Irma Lair (stepdaughter in comics, biological daughter in TV series)
- Chris Lair (stepson in comics, biological Son in TV series)
- Her best girlfriends are Mary & Jane Green.
- She is voiced by Candi Milo, the same voice actress as Irma.